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Manufacturer Vitamin K2 Mk4 Powder 98% 1.3% Menaquinone-4
Vitamin K2 MK4: Essential for Health
Vitamin K2 MK4 is one of the most common forms of vitamin K2. It is not only naturally synthesized by the human body but also plays a crucial role in regulating brain nerve function and specific gene expression, highlighting its significance for overall health. Multiple studies have demonstrated that vitamin K2 MK4 is essential for maintaining bone health. Additionally, supplementation can enhance tooth strength, promote dentin regeneration, and help prevent and treat cavities.
Given its safety and importance in bone and vascular health, the United States Pharmacopeia (USP) approved vitamin K2 MK4 as a dietary supplement in 2021, making it widely applicable in health products, functional foods, and fortified nutrition.
As an essential nutrient, vitamin K2 MK4 regulates various physiological functions. When the body's natural synthesis is insufficient, appropriate supplementation becomes necessary. However, to achieve optimal benefits, it is crucial to choose high-content, highly active vitamin K2 MK4 ingredients.
Test report
| ITEM | STANDARD | TEST RESULT |
| Vitamin K2(Menaquinone-4) | ≥98.0% | 98.06% |
| Physical & Chemical | ||
| Appearance | Yellow crystals powder | Yellow crystals powder |
| Clarity in Hexane | Clear and Yellow | Complies |
| Loss on Drying | ≤6.0% | 3.43% |
| Solubility | Easily soluble in n-hexane, soluble in ethanol, slightly soluble in methanol, almost insoluble in water | Complies |
| Identification | ||
| -Ethanol+Potassium Hydroxide | Blue | Complies |
| -Ethanol+Sodium Hydrosulfite | Yellow | Complies |
| -Absorption in Isooctane | 325nm~327nm | Complies |
| -Absorbance Ratio A1/A2 | 0.32-0.38 | 0.36 |
| Melting Point | ≥35.0℃ | 37℃ |
| Water | ≤ 0.5% | 0.3% |
| Residue On Ignition | ≤ 0.10% | 0.02% |
| Heavy Metal | ||
| Total Heavy Metals | ≤20ppm | Complies |
| As | < 2ppm | Complies |
| Menaquinone | Not appear royal purple | Not appear royal purple |
| Solvent Residue | ||
| Ethanol | ≤ 0.3% | 0.27% |
| Other Related Substances ratio | 0.01% | Complies |
Mechanism of Action
The mechanism of menaquinone (vitamin K2) is similar to that of vitamin K1, as it assists γ-glutamyl carboxylase in converting glutamic acid (Glu) into γ-carboxyglutamic acid (Gla). This process is essential for the formation of Gla-containing proteins (Gla-proteins), such as:
● Osteocalcin: Involved in bone mineralization.
● GAS6: Regulates cell proliferation.
● Thrombin and anticoagulant proteins: Maintain blood homeostasis.
Application areas
Vitamin K2 MK4 is mainly used in the field of health products, mainly for osteoporosis.
