Factory Directly Supply Vitamin K2 MK7/Menaquinone-7 Powder

Vitamin K2, also known as menaquinone, is a fat-soluble vitamin and one of the essential nutrients for the human body. It is primarily synthesized by intestinal bacteria and is also found in animal products and fermented foods such as animal liver, fermented dairy products, and cheese. Among these, natto is the richest source of Vitamin K2.

As a cofactor for γ-glutamyl carboxylase, Vitamin K2 activates several vitamin K-dependent proteins, playing a crucial role in cardiovascular and bone health.

Vitamin K2 (menaquinone-7) is found in fermented foods and animal products, and it can also be produced by intestinal bacteria. It refers to a class of compounds containing a 2-methyl-1,4-naphthoquinone core structure, with terpene side chains at the C3 position, which contain varying numbers of isoprenoid units. It is abundant in the liver.

Vitamin K2 plays a crucial role in bone metabolism. It is an essential nutrient for the carboxylation of osteocalcin, a key protein secreted by osteoblasts. When activated, osteocalcin promotes calcium absorption and incorporation into the bone matrix, enhancing bone strength. Additionally, Vitamin K2 works synergistically with Vitamin D3 to help inhibit the activity of osteoclasts (cells responsible for bone resorption).

Vitamin K2 also activates matrix GLA protein (MGP), which helps remove excess calcium accumulated in soft tissues such as arteries and veins. This is particularly important because about 20% of the components in atherosclerotic plaques are calcium.

In healthy individuals with a balanced diet, Vitamin K1 deficiency leading to coagulation issues is rare. However, people who favor Western diets may not get enough Vitamin K2 from their food. Serum Vitamin K2 levels are not a reliable indicator, but the under-carboxylated osteocalcin can serve as an indirect marker of Vitamin K2 levels, which will be more widely used in the future. Vitamin K2 deficiency may lead to reduced bone mineralization, osteoporosis, and even increase the risk of heart disease. Moreover, the use of broad-spectrum antibiotics can also lead to Vitamin K2 deficiency.

Menaquinone-7 (MK-7) is a long-chain form of Vitamin K, primarily sourced from fermented foods, especially natto (a fermented soybean product). MK-7 is formed during fermentation and has two major advantages: it remains in the body for a longer duration, with a longer half-life, meaning only one convenient daily dose is required to meet the body's needs. Research indicates that MK-7 can suppress pro-inflammatory markers, helping to prevent autoimmune diseases such as rheumatoid arthritis.