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CAS 59870-68-7 Licorice Extract Glabridin Powder
Characteristics and Sources of Liquiritin
Basic Characteristics
Source: Extracted from the roots of Glycyrrhiza glabra (licorice), liquiritin is one of the active flavonoid compounds in licorice.
Physical Properties:
Solubility:
● Insoluble in water
● Easily soluble in organic solvents such as ethanol and propylene glycol
Safety:
● All-natural extraction, free from pollutants, with no irritating side effects
Core Benefits
Whitening Mechanism:
● Directly inhibits tyrosinase activity, blocking melanin synthesis
● Scavenges free radicals, reducing pigmentation caused by oxidative stress
Anti-aging Effects:
● Protects collagen, reducing UV-induced photoaging
● Improves skin roughness, enhancing skin radiance
Industry Position:
Due to its highly effective whitening properties, liquiritin is referred to as the "whitening gold" and is a core active ingredient in high-end skincare products.
Whitening and Skincare Mechanisms of Liquiritin
1.Whitening Mechanism
Competitive Inhibition of Tyrosinase:
● Liquiritin, with a molecular structure similar to tyrosine, can preferentially bind to tyrosinase.
● It blocks the catalytic action of tyrosinase on tyrosine, reducing the generation of melanin precursors by more than 70%.
● By inhibiting melanin synthesis from the source, it achieves "targeted depigmentation."
2.Multiple Skincare Benefits
Collagen Activation:
● Stimulates fibroblast activity, increasing Type I collagen synthesis by 30%-50%.
● Improves skin laxity and reduces wrinkles.
Antioxidant Defense:
● The flavonoids in liquiritin can scavenge free radicals (ORAC value of 8000 μmol TE/g).
● Reduces UV-induced DNA oxidative damage.
Anti-inflammatory Repair:
● Inhibits inflammatory factors such as COX-2 and PGE2.
● Relieves skin redness and sensitivity.
3.Synergistic Biological Activity
Vitamin C Synergistic Effect:
● The naturally occurring vitamin C in licorice enhances the antioxidant network.
● Promotes melanin metabolism, achieving "blockage + metabolism" dual-pathway whitening.
Application Value:
As a safe and effective natural ingredient, liquiritin is widely used in high-end whitening serums, anti-aging creams, and repair skincare products, offering both immediate effects and long-term care benefits.
Multifaceted Application Value of Liquiritin
Cosmetics Field
Core Benefits:
● Targeted Whitening: Inhibits tyrosinase activity, reducing melanin production (2-3 times more effective than arbutin).
● Anti-Photoaging: Neutralizes UV-induced free radicals, reducing collagen degradation by over 40%.
● Anti-inflammatory and Soothing: Inhibits the release of pro-inflammatory factors like IL-6, improving skin sensitivity.
Product Forms:
● High-end whitening serums, anti-aging creams
● Sunscreen and repair products (SPF enhancers)
Health Food Field
Weight Management:
● Modulates leptin sensitivity, reducing appetite by 15%-20%.
● Promotes fat oxidation (clinical trials show a reduction in waist circumference by 3-5cm in 12 weeks).
Metabolic Support:
● Improves insulin resistance (HOMA-IR index decreases by 1.2-1.5 points).
Technical Advantages:
● Cosmetics-grade purity ≥98% (HPLC tested).
● Overcomes water solubility issues with nano-encapsulation technology (80% improvement in bioavailability).
