CAS 489-32-7 Icariin 98% Powder

Icariin, the primary bioactive component of plants in the Epimedium genus, is a prenylated flavonoid glycoside with significant pharmacological activity. This light-yellow needle-like crystalline compound is mainly extracted from the dried stems and leaves of various Epimedium species, such as Epimedium sagittatum and Epimedium pubescens. It exhibits distinctive solubility characteristics—soluble in ethanol and ethyl acetate, but insoluble in ether, benzene, and chloroform.

Epimedium plants contain an exceptionally rich chemical profile: the aerial parts are predominantly composed of flavonoids, while the underground parts are abundant in both flavonoids and alkaloids. In addition, they also contain lignans, anthraquinones, polysaccharides, and hundreds of other bioactive compounds, with the composition varying significantly among species.

Modern research has shown that icariin exerts multi-target pharmacological effects: it improves microcirculation in the cardiovascular and cerebrovascular systems, promotes hematopoietic function, regulates the immune system, and balances bone metabolism. Building upon the traditional Chinese medicine use of Epimedium for “kidney reinforcement and yang enhancement,” icariin has also demonstrated notable anti-aging properties. This highlights the “multi-component, multi-target, and multi-pathway” mechanisms characteristic of natural medicines.

● Enhancement of Sexual Function: Stimulates semen secretion and increases libido.

● Mechanism of Action: Enhances sexual function indirectly by promoting seminal vesicle filling, which stimulates sensory nerves.

● Improving Immunodeficiency: Increases T cell count, antibody levels, and macrophage activity in individuals with kidney deficiency.

● Immune Balance Modulation: Enhances overall immune function through kidney-tonifying effects.

● Cellular Protection: Prolongs cell life cycle and delays aging processes.

● Metabolic Optimization: Regulates endocrine and immune systems, improving organ function.

● Anti-Myocardial Ischemia: Alleviates myocardial ischemia caused by posterior pituitary extract in rats.

● Antihypertensive Effects: Demonstrates significant blood pressure-lowering properties.

Hematopoiesis Promotion: Improves blood circulation and supports blood cell formation.

Bone Strengthening: Regulates bone metabolism and helps maintain skeletal health.