99% Spermidine Trihydrochloride Powder

Spermidine is a natural polyamine, widely found in living organisms, and is biosynthesized from putrescine (butane diamine) and adenosylmethionine. It exhibits various biological activities, including inhibiting neuronal nitric oxide synthase (nNOS), binding to and precipitating DNA, purifying DNA-binding proteins, and stimulating T4 polynucleotide kinase activity. Supplementing spermidine can activate autophagy, help repair damaged cells, and eliminate toxic proteins associated with neurodegenerative diseases. Spermidine also has anti-aging effects, helps prevent Alzheimer's disease, and protects the nervous system.

Spermidine hydrochloride is a white crystalline powder, odorless, easily soluble in water, and slightly soluble in ethanol and acetone. Its chemical formula is C₅H₁₃NO₂·HCl, and its molecular weight is 153.62. As a quaternary ammonium salt, spermidine hydrochloride is an important alkaloid with significant physiological and pharmacological effects. It is widely used in medicine, food, cosmetics, and agriculture, and is an important functional molecule with a broad range of applications.

Spermidine hydrochloride is used as a hepatoprotective agent, improving liver function and reducing liver damage. It is also used to treat conditions such as high cholesterol, high triglyceridemia, and cardiovascular diseases. It works by lowering plasma homocysteine (Hcy) levels, thereby reducing the risk of cardiovascular diseases. Studies have shown that spermidine hydrochloride promotes Hcy metabolism and significantly lowers plasma Hcy levels, which helps reduce cardiovascular disease risks. For example, one study divided participants into a spermidine hydrochloride supplementation group and a placebo group. The results showed that the supplementation group had a significant reduction in plasma Hcy levels and a notable decrease in cardiovascular disease risk. Other studies also support its role in reducing cardiovascular disease risk.

Spermidine hydrochloride is used as a flavor enhancer and moisturizer in food, improving taste and maintaining humidity. Additionally, it is used as a feed additive to enhance animal growth and muscle mass.

Spermidine hydrochloride serves as a moisturizer and antioxidant, helping to retain skin moisture and reduce free radical damage. It is also used in sunscreens to mitigate UV damage to the skin.

Spermidine hydrochloride acts as a plant growth regulator, promoting crop growth and increasing yield.