Wholesale N-Acetyl-L-Glutamine Powder Food Grade CAS 2490-97-3
N-Acetyl-L-Glutamine: Product Introduction
N-Acetyl-L-glutamine is an amino acid derivative formed by the conjugation of glutamine with an acetyl group. Structurally, it resembles glutamine; however, the addition of the acetyl group endows it with a critical capability: the efficient penetration of the blood-brain barrier. This ability to traverse the blood-brain barrier gives N-acetyl-L-glutamine a unique advantage in the therapeutic treatment of the nervous system. It acts directly upon brain cells, providing the brain with essential nutrients and protection.
Why Choose YTBIO N-Acetyl-L-Glutamine?
We are a professional manufacturer with over 12 years of experience supplying high-stability amino acid raw materials for sports nutrition, intestinal health and brain support supplements. Our production facility is certified with cGMP, FSSC22000, BRC, HACCP, HALAL, KOSHER, ISO9001 & ISO22000, fully meeting international food safety specifications.
Our N-Acetyl-L-Glutamine is produced by advanced acylation synthesis and recrystallization purification, standard 99% HPLC white crystalline powder. Compared with ordinary L-Glutamine, it features superior acid resistance, heat stability and better intestinal absorption efficiency.
Mechanism of Action:
N-acetyl-L-glutamine is capable of crossing the human blood-brain barrier. Upon entering brain tissue, and under the action of specific enzymes, it breaks down into two critically important neuroactive substances: glutamate and gamma-aminobutyric acid (GABA). Together, these two substances modulate the functions of the body's nervous system; they serve to ameliorate impairments in neurological function and can thereby enhance overall brain function.
N-Acetyl-L-Glutamine vs. Glutamine
Superior Stability: Resistant to high temperatures, acids, and bases; does not decompose easily, resulting in a longer shelf life.
Excellent Water Solubility: Higher solubility than glutamine, facilitating its incorporation into pharmaceutical formulations and beverages.
High Bioavailability: Acetylation modification enhances absorption efficiency and extends the duration of action.
N-Acetyl-L-Glutamine Test Report
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ITEM |
STANDARD |
TEST RESULT |
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Physical & Chemical |
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Appearance |
Powder |
Complies |
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Color |
White fine Powder |
Complies |
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Particle Size |
100% pass 80 mesh |
Complies |
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Oder |
Characteristic |
Complies |
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Taste |
Characteristic |
Complies |
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Loss on Drying |
≤5.0% |
2.20% |
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Residue on Ignition |
≤0.1% |
0.05% |
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Residual acetone |
≤0.1% |
Complies |
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Residual Ethanol |
≤0.5% |
Complies |
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Heave Mentals |
≤10ppm |
Complies |
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Na |
≤0.1% |
<0.1% |
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Pb |
≤3 ppm |
Complies |
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Microbiological Test |
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Total Plate |
<1000CFU/g |
Complies |
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Yeast & Mold |
<100 CFU /g |
Complies |
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E. Coli |
Negative |
Complies |
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Salmonella |
Negative |
Complies |
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Conclusion |
Conform with specification |
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Storage |
Store in cool and dry places. Keep away from strong light and heat |
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Packing |
By 25kgs/Drum, inner by double plastic bag |
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Shelf Life |
24 months under the above condition,and in it’s original package |
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Health Benefits
Promoting Neuronal Metabolism: N-acetyl-L-glutamine serves as an energy precursor for brain cells, enhancing their utilization of glucose and ameliorating neuronal dysfunction resulting from ischemia and hypoxia. It is widely distributed throughout the body and is capable of crossing the blood-brain barrier, with particularly high concentrations found in the brain, liver, and kidneys. Within renal tubular cells, it undergoes enzymatic hydrolysis by glutaminase—releasing ammonia and converting into acetylglutamic acid. The released ammonia is secreted and excreted via the renal tubules, while the acetylglutamic acid is reabsorbed to participate in the body's metabolic processes.
Regulation of Neurotransmitter Transmission: Upon crossing the blood-brain barrier, N-acetyl-L-glutamine breaks down into glutamate and gamma-aminobutyric acid (GABA). Glutamate participates in information transmission within the central nervous system, while GABA counteracts the excitatory effects of glutamate and improves neuronal metabolism, thereby enhancing brain function.
Combating Oxidative Stress: Mitigating oxidative damage following neuronal injury, reducing inflammatory responses, and creating conditions conducive to repair.
Application Areas Overview
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N-Acetyl-L-Glutamine Application Fields |
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Application Field |
Core Application Scenarios |
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Pharmaceutical Field |
1. Neurological medication: for brain trauma, hepatic coma, memory loss, Alzheimer's disease, etc. |
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Functional Food & Sports Nutrition |
1. Sports recovery supplements: promote muscle repair, relieve training fatigue, improve endurance |
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Cosmetics & Skincare Products |
1. Skin repair and moisturizing: promote stratum corneum repair, soothe sensitivity and redness, improve moisturizing power |
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